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Stanford Medicine detecting antibodies against coronavirus in plasma: research
2020年04月30日 06:33:46 作者:International Daily 来源: 字号 打印 关闭

SAN FRANCISCO, April 12 (Xinhua) -- A large team of Stanford Medicine scientists have developed a test to detect antibodies against the novel coronavirus in blood samples.In contrast to current diagnostic tests for COVID-19, which detect genetic material from the virus in respiratory secretions, the new test led by Scott Boyd, associate professor of pathology, screens for antibodies to the virus in plasma, the liquid in blood, to provide information about a person's immune response to an infection.It detects two different types of antibodies: IgM antibodies, which are made early in an immune response and whose levels usually quickly wane, and IgG antibodies, whose levels rise more slowly after infection but usually persist longer, Stanford Medicine said in a statement on Friday."There are limited data out of China and Europe showing that this appears to be the response pattern followed with this virus," said Thomas Montine, professor and chair of pathology at the School of Medicine. "No one has had this long enough to know how long after infection the antibodies persist." The test, which takes two to three days for results, was launched on April 6 at Stanford Health Care. Stanford Health Care is able to test 500 samples per day, according to the statement."It's essential to have the right tools to understand the biology of the novel coronavirus," said Lloyd Minor, dean of the Stanford University School of Medicine. "This test takes us one step closer to answering the many public health questions about COVID-19.""Serological testing gives us a more comprehensive view of what's happening in an individual who is infected, or has been infected, with the virus," agreed Montine.Serological testing can answer many questions that cannot be addressed with the current COVID-19 diagnostic test, which uses polymerase chain reaction methods to detect viral genetic material."That approach could be very important in this period when we don't have vaccines or other definitive therapies," said Montine. "We thought this was an urgent medical need, and the usual supply chains were unreliable, so we decided to build our own."

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